Menthol salicylate

Generic Name: Menthol salicylate
Brand Name: Mentodic®
Dosage Form: 30g ointment (Each 100 g of ointment contains 14 g Methyl Salicylate and 10 g Menthol)
Pharmacological Category: Topical analgesics
Therapeutic Category: Anti-inflammatory drugs
Pregnancy Category: category B

Pharmacology

Methyl salicylate is a salicylic acid derivative.Salicylates inhibit cyclooxygenase, thereby reducing the formation of prostaglandins.

Pharmacokinetics:

• May be absorbed through intact skin.

• The absorption of topical salicylates is proportional to the surface area involved, duration of exposure, concentration and skin integrity.
• Absorption characteristics of salicylates vary with the dose, formulation and route of administration.
• Percutaneous absorption is enhanced by exercise, heat, occlusion, or disruption of the integrity of the skin or application to large areas of skin
• Both the rate and extent of absorption increases after repeated application;increasing the bioavailability.
• Methylsalicylateis extensively metabolised to salicylic acid in the dermal and subcutaneous tissues after topical application
• At therapeutic levels, the half life of salicylates is 2-4 hours.
• As salicylate level increase into the toxic range, the half-life can be greater than 18 hours.

Indications:

• Provide symptomatic relief for mild to moderate muscular and joint aches and pains, muscle cramps, shoulder aches and stiff neck
• For the temporary relief of pain associated with rheumatism, arthritis, neuralgia, sprains and strains of joints and muscles, lumbago and fibrositis

Contraindications:

• Do not use in patients with aspirin or salicylate idiosyncrasy.
• Hypersensitivity to any of the ingredients in the product.

Precautions:

• Initially apply a small amount to a limited skin area and observe whether there is discomfort or itch before applying to a larger skin area. Discontinue use if irritation develops.
• For external use only; not to be taken.
• Avoid contact with the eyes and mucous membranes.
• Do not apply to open wounds or damaged skin.
• Avoid excessive use during pregnancy and lactation
• Do not apply over large areas of the body or bandageor use with heating pads.

Drug Interactions:

• This product contains methyl salicylate and when applied or rubbed on to the skin, can be absorbed through the skin into the blood. For patients taking warfarin, excessive application on to the skin for muscle or joints pains may increase the chances of bleeding

Side Effects:

• Headache, dizziness, nausea and vomiting, skin irritation, contact dermatitis, rash, itching, redness or swelling, burning or stinging sensation may occur.
• May cause hypersensitivity/allergic reactions in some individuals with sensitive skin

Storage:

• Store below 30 C°
• Protect from light and freezing

Packing:

Methyl salicylate ointment : 1 tube/box-30g

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Image: 
Brand Name: 

Mentodic®

Dosage Form: 

30g ointment (Each 100 g of ointment contains 14 g Methyl Salicylate and 10 g Menthol)

Pharmacological Category: 

Topical analgesics

Therapeutic Category: 

Anti-inflammatory drugs

Pregnancy Category: 

category B

Methyl salicylate is a salicylic acid derivative.Salicylates inhibit cyclooxygenase, thereby reducing the formation of prostaglandins.

Pharmacokinetics: 

• May be absorbed through intact skin.

• The absorption of topical salicylates is proportional to the surface area involved, duration of exposure, concentration and skin integrity.
• Absorption characteristics of salicylates vary with the dose, formulation and route of administration.
• Percutaneous absorption is enhanced by exercise, heat, occlusion, or disruption of the integrity of the skin or application to large areas of skin
• Both the rate and extent of absorption increases after repeated application;increasing the bioavailability.
• Methylsalicylateis extensively metabolised to salicylic acid in the dermal and subcutaneous tissues after topical application
• At therapeutic levels, the half life of salicylates is 2-4 hours.
• As salicylate level increase into the toxic range, the half-life can be greater than 18 hours.

Indications: 

• Provide symptomatic relief for mild to moderate muscular and joint aches and pains, muscle cramps, shoulder aches and stiff neck
• For the temporary relief of pain associated with rheumatism, arthritis, neuralgia, sprains and strains of joints and muscles, lumbago and fibrositis

Contraindications: 

• Do not use in patients with aspirin or salicylate idiosyncrasy.
• Hypersensitivity to any of the ingredients in the product.

Precautions: 

• Initially apply a small amount to a limited skin area and observe whether there is discomfort or itch before applying to a larger skin area. Discontinue use if irritation develops.
• For external use only; not to be taken.
• Avoid contact with the eyes and mucous membranes.
• Do not apply to open wounds or damaged skin.
• Avoid excessive use during pregnancy and lactation
• Do not apply over large areas of the body or bandageor use with heating pads.

Drug Interactions: 

• This product contains methyl salicylate and when applied or rubbed on to the skin, can be absorbed through the skin into the blood. For patients taking warfarin, excessive application on to the skin for muscle or joints pains may increase the chances of bleeding

Side Effects: 

• Headache, dizziness, nausea and vomiting, skin irritation, contact dermatitis, rash, itching, redness or swelling, burning or stinging sensation may occur.
• May cause hypersensitivity/allergic reactions in some individuals with sensitive skin

Storage: 

• Store below 30 C°
• Protect from light and freezing

Packing: 

Methyl salicylate ointment : 1 tube/box-30g

PDF: 
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• Hypersensitivity to any of the ingredients in the product.

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• For the temporary relief of pain associated with rheumatism, arthritis, neuralgia, sprains and strains of joints and muscles, lumbago and fibrositis

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• For the temporary relief of pain associated with rheumatism, arthritis, neuralgia, sprains and strains of joints and muscles, lumbago and fibrositis

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• May be absorbed through intact skin.

• The absorption of topical salicylates is proportional to the surface area involved, duration of exposure, concentration and skin integrity.
• Absorption characteristics of salicylates vary with the dose, formulation and route of administration.
• Percutaneous absorption is enhanced by exercise, heat, occlusion, or disruption of the integrity of the skin or application to large areas of skin
• Both the rate and extent of absorption increases after repeated application;increasing the bioavailability.
• Methylsalicylateis extensively metabolised to salicylic acid in the dermal and subcutaneous tissues after topical application
• At therapeutic levels, the half life of salicylates is 2-4 hours.
• As salicylate level increase into the toxic range, the half-life can be greater than 18 hours.

[view] =>

• May be absorbed through intact skin.

• The absorption of topical salicylates is proportional to the surface area involved, duration of exposure, concentration and skin integrity.
• Absorption characteristics of salicylates vary with the dose, formulation and route of administration.
• Percutaneous absorption is enhanced by exercise, heat, occlusion, or disruption of the integrity of the skin or application to large areas of skin
• Both the rate and extent of absorption increases after repeated application;increasing the bioavailability.
• Methylsalicylateis extensively metabolised to salicylic acid in the dermal and subcutaneous tissues after topical application
• At therapeutic levels, the half life of salicylates is 2-4 hours.
• As salicylate level increase into the toxic range, the half-life can be greater than 18 hours.

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• For external use only; not to be taken.
• Avoid contact with the eyes and mucous membranes.
• Do not apply to open wounds or damaged skin.
• Avoid excessive use during pregnancy and lactation
• Do not apply over large areas of the body or bandageor use with heating pads.

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• For external use only; not to be taken.
• Avoid contact with the eyes and mucous membranes.
• Do not apply to open wounds or damaged skin.
• Avoid excessive use during pregnancy and lactation
• Do not apply over large areas of the body or bandageor use with heating pads.

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• May cause hypersensitivity/allergic reactions in some individuals with sensitive skin

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• May cause hypersensitivity/allergic reactions in some individuals with sensitive skin

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Methyl salicylate is a salicylic acid derivative.Salicylates inhibit cyclooxygenase, thereby reducing the formation of prostaglandins.

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• May be absorbed through intact skin.

• The absorption of topical salicylates is proportional to the surface area involved, duration of exposure, concentration and skin integrity.
• Absorption characteristics of salicylates vary with the dose, formulation and route of administration.
• Percutaneous absorption is enhanced by exercise, heat, occlusion, or disruption of the integrity of the skin or application to large areas of skin
• Both the rate and extent of absorption increases after repeated application;increasing the bioavailability.
• Methylsalicylateis extensively metabolised to salicylic acid in the dermal and subcutaneous tissues after topical application
• At therapeutic levels, the half life of salicylates is 2-4 hours.
• As salicylate level increase into the toxic range, the half-life can be greater than 18 hours.

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• May be absorbed through intact skin.

• The absorption of topical salicylates is proportional to the surface area involved, duration of exposure, concentration and skin integrity.
• Absorption characteristics of salicylates vary with the dose, formulation and route of administration.
• Percutaneous absorption is enhanced by exercise, heat, occlusion, or disruption of the integrity of the skin or application to large areas of skin
• Both the rate and extent of absorption increases after repeated application;increasing the bioavailability.
• Methylsalicylateis extensively metabolised to salicylic acid in the dermal and subcutaneous tissues after topical application
• At therapeutic levels, the half life of salicylates is 2-4 hours.
• As salicylate level increase into the toxic range, the half-life can be greater than 18 hours.

) [#title] => [#description] => [#children] =>

• May be absorbed through intact skin.

• The absorption of topical salicylates is proportional to the surface area involved, duration of exposure, concentration and skin integrity.
• Absorption characteristics of salicylates vary with the dose, formulation and route of administration.
• Percutaneous absorption is enhanced by exercise, heat, occlusion, or disruption of the integrity of the skin or application to large areas of skin
• Both the rate and extent of absorption increases after repeated application;increasing the bioavailability.
• Methylsalicylateis extensively metabolised to salicylic acid in the dermal and subcutaneous tissues after topical application
• At therapeutic levels, the half life of salicylates is 2-4 hours.
• As salicylate level increase into the toxic range, the half-life can be greater than 18 hours.

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• May be absorbed through intact skin.

• The absorption of topical salicylates is proportional to the surface area involved, duration of exposure, concentration and skin integrity.
• Absorption characteristics of salicylates vary with the dose, formulation and route of administration.
• Percutaneous absorption is enhanced by exercise, heat, occlusion, or disruption of the integrity of the skin or application to large areas of skin
• Both the rate and extent of absorption increases after repeated application;increasing the bioavailability.
• Methylsalicylateis extensively metabolised to salicylic acid in the dermal and subcutaneous tissues after topical application
• At therapeutic levels, the half life of salicylates is 2-4 hours.
• As salicylate level increase into the toxic range, the half-life can be greater than 18 hours.

[#printed] => 1 ) [#title] => [#description] => [#children] =>
Pharmacokinetics: 

• May be absorbed through intact skin.

• The absorption of topical salicylates is proportional to the surface area involved, duration of exposure, concentration and skin integrity.
• Absorption characteristics of salicylates vary with the dose, formulation and route of administration.
• Percutaneous absorption is enhanced by exercise, heat, occlusion, or disruption of the integrity of the skin or application to large areas of skin
• Both the rate and extent of absorption increases after repeated application;increasing the bioavailability.
• Methylsalicylateis extensively metabolised to salicylic acid in the dermal and subcutaneous tissues after topical application
• At therapeutic levels, the half life of salicylates is 2-4 hours.
• As salicylate level increase into the toxic range, the half-life can be greater than 18 hours.

[#printed] => 1 ) [field_indications] => Array ( [#type_name] => product [#context] => full [#field_name] => field_indications [#post_render] => Array ( [0] => content_field_wrapper_post_render ) [#weight] => 5 [field] => Array ( [#description] => [items] => Array ( [0] => Array ( [#formatter] => default [#node] => stdClass Object *RECURSION* [#type_name] => product [#field_name] => field_indications [#weight] => 0 [#theme] => text_formatter_default [#item] => Array ( [value] => • Provide symptomatic relief for mild to moderate muscular and joint aches and pains, muscle cramps, shoulder aches and stiff neck • For the temporary relief of pain associated with rheumatism, arthritis, neuralgia, sprains and strains of joints and muscles, lumbago and fibrositis [format] => 1 [safe] =>

• Provide symptomatic relief for mild to moderate muscular and joint aches and pains, muscle cramps, shoulder aches and stiff neck
• For the temporary relief of pain associated with rheumatism, arthritis, neuralgia, sprains and strains of joints and muscles, lumbago and fibrositis

[#delta] => 0 ) [#title] => [#description] => [#theme_used] => 1 [#printed] => 1 [#type] => [#value] => [#prefix] => [#suffix] => [#children] =>

• Provide symptomatic relief for mild to moderate muscular and joint aches and pains, muscle cramps, shoulder aches and stiff neck
• For the temporary relief of pain associated with rheumatism, arthritis, neuralgia, sprains and strains of joints and muscles, lumbago and fibrositis

) [#title] => [#description] => [#children] =>

• Provide symptomatic relief for mild to moderate muscular and joint aches and pains, muscle cramps, shoulder aches and stiff neck
• For the temporary relief of pain associated with rheumatism, arthritis, neuralgia, sprains and strains of joints and muscles, lumbago and fibrositis

[#printed] => 1 ) [#single] => 1 [#attributes] => Array ( ) [#required] => [#parents] => Array ( ) [#tree] => [#context] => full [#page] => 1 [#field_name] => field_indications [#title] => Indications [#access] => 1 [#label_display] => above [#teaser] => [#node] => stdClass Object *RECURSION* [#type] => content_field [#children] =>

• Provide symptomatic relief for mild to moderate muscular and joint aches and pains, muscle cramps, shoulder aches and stiff neck
• For the temporary relief of pain associated with rheumatism, arthritis, neuralgia, sprains and strains of joints and muscles, lumbago and fibrositis

[#printed] => 1 ) [#title] => [#description] => [#children] =>
Indications: 

• Provide symptomatic relief for mild to moderate muscular and joint aches and pains, muscle cramps, shoulder aches and stiff neck
• For the temporary relief of pain associated with rheumatism, arthritis, neuralgia, sprains and strains of joints and muscles, lumbago and fibrositis

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• Do not use in patients with aspirin or salicylate idiosyncrasy.
• Hypersensitivity to any of the ingredients in the product.

[#delta] => 0 ) [#title] => [#description] => [#theme_used] => 1 [#printed] => 1 [#type] => [#value] => [#prefix] => [#suffix] => [#children] =>

• Do not use in patients with aspirin or salicylate idiosyncrasy.
• Hypersensitivity to any of the ingredients in the product.

) [#title] => [#description] => [#children] =>

• Do not use in patients with aspirin or salicylate idiosyncrasy.
• Hypersensitivity to any of the ingredients in the product.

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• Do not use in patients with aspirin or salicylate idiosyncrasy.
• Hypersensitivity to any of the ingredients in the product.

[#printed] => 1 ) [#title] => [#description] => [#children] =>
Contraindications: 

• Do not use in patients with aspirin or salicylate idiosyncrasy.
• Hypersensitivity to any of the ingredients in the product.

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• Initially apply a small amount to a limited skin area and observe whether there is discomfort or itch before applying to a larger skin area. Discontinue use if irritation develops.
• For external use only; not to be taken.
• Avoid contact with the eyes and mucous membranes.
• Do not apply to open wounds or damaged skin.
• Avoid excessive use during pregnancy and lactation
• Do not apply over large areas of the body or bandageor use with heating pads.

[#delta] => 0 ) [#title] => [#description] => [#theme_used] => 1 [#printed] => 1 [#type] => [#value] => [#prefix] => [#suffix] => [#children] =>

• Initially apply a small amount to a limited skin area and observe whether there is discomfort or itch before applying to a larger skin area. Discontinue use if irritation develops.
• For external use only; not to be taken.
• Avoid contact with the eyes and mucous membranes.
• Do not apply to open wounds or damaged skin.
• Avoid excessive use during pregnancy and lactation
• Do not apply over large areas of the body or bandageor use with heating pads.

) [#title] => [#description] => [#children] =>

• Initially apply a small amount to a limited skin area and observe whether there is discomfort or itch before applying to a larger skin area. Discontinue use if irritation develops.
• For external use only; not to be taken.
• Avoid contact with the eyes and mucous membranes.
• Do not apply to open wounds or damaged skin.
• Avoid excessive use during pregnancy and lactation
• Do not apply over large areas of the body or bandageor use with heating pads.

[#printed] => 1 ) [#single] => 1 [#attributes] => Array ( ) [#required] => [#parents] => Array ( ) [#tree] => [#context] => full [#page] => 1 [#field_name] => field_precautions [#title] => Precautions [#access] => 1 [#label_display] => above [#teaser] => [#node] => stdClass Object *RECURSION* [#type] => content_field [#children] =>

• Initially apply a small amount to a limited skin area and observe whether there is discomfort or itch before applying to a larger skin area. Discontinue use if irritation develops.
• For external use only; not to be taken.
• Avoid contact with the eyes and mucous membranes.
• Do not apply to open wounds or damaged skin.
• Avoid excessive use during pregnancy and lactation
• Do not apply over large areas of the body or bandageor use with heating pads.

[#printed] => 1 ) [#title] => [#description] => [#children] =>
Precautions: 

• Initially apply a small amount to a limited skin area and observe whether there is discomfort or itch before applying to a larger skin area. Discontinue use if irritation develops.
• For external use only; not to be taken.
• Avoid contact with the eyes and mucous membranes.
• Do not apply to open wounds or damaged skin.
• Avoid excessive use during pregnancy and lactation
• Do not apply over large areas of the body or bandageor use with heating pads.

[#printed] => 1 ) [field_drug_interactions] => Array ( [#type_name] => product [#context] => full [#field_name] => field_drug_interactions [#post_render] => Array ( [0] => content_field_wrapper_post_render ) [#weight] => 9 [field] => Array ( [#description] => [items] => Array ( [0] => Array ( [#formatter] => default [#node] => stdClass Object *RECURSION* [#type_name] => product [#field_name] => field_drug_interactions [#weight] => 0 [#theme] => text_formatter_default [#item] => Array ( [value] => • This product contains methyl salicylate and when applied or rubbed on to the skin, can be absorbed through the skin into the blood. For patients taking warfarin, excessive application on to the skin for muscle or joints pains may increase the chances of bleeding [format] => 1 [safe] =>

• This product contains methyl salicylate and when applied or rubbed on to the skin, can be absorbed through the skin into the blood. For patients taking warfarin, excessive application on to the skin for muscle or joints pains may increase the chances of bleeding

[#delta] => 0 ) [#title] => [#description] => [#theme_used] => 1 [#printed] => 1 [#type] => [#value] => [#prefix] => [#suffix] => [#children] =>

• This product contains methyl salicylate and when applied or rubbed on to the skin, can be absorbed through the skin into the blood. For patients taking warfarin, excessive application on to the skin for muscle or joints pains may increase the chances of bleeding

) [#title] => [#description] => [#children] =>

• This product contains methyl salicylate and when applied or rubbed on to the skin, can be absorbed through the skin into the blood. For patients taking warfarin, excessive application on to the skin for muscle or joints pains may increase the chances of bleeding

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• This product contains methyl salicylate and when applied or rubbed on to the skin, can be absorbed through the skin into the blood. For patients taking warfarin, excessive application on to the skin for muscle or joints pains may increase the chances of bleeding

[#printed] => 1 ) [#title] => [#description] => [#children] =>
Drug Interactions: 

• This product contains methyl salicylate and when applied or rubbed on to the skin, can be absorbed through the skin into the blood. For patients taking warfarin, excessive application on to the skin for muscle or joints pains may increase the chances of bleeding

[#printed] => 1 ) [field_side_effects] => Array ( [#type_name] => product [#context] => full [#field_name] => field_side_effects [#post_render] => Array ( [0] => content_field_wrapper_post_render ) [#weight] => 10 [field] => Array ( [#description] => [items] => Array ( [0] => Array ( [#formatter] => default [#node] => stdClass Object *RECURSION* [#type_name] => product [#field_name] => field_side_effects [#weight] => 0 [#theme] => text_formatter_default [#item] => Array ( [value] => • Headache, dizziness, nausea and vomiting, skin irritation, contact dermatitis, rash, itching, redness or swelling, burning or stinging sensation may occur. • May cause hypersensitivity/allergic reactions in some individuals with sensitive skin [format] => 1 [safe] =>

• Headache, dizziness, nausea and vomiting, skin irritation, contact dermatitis, rash, itching, redness or swelling, burning or stinging sensation may occur.
• May cause hypersensitivity/allergic reactions in some individuals with sensitive skin

[#delta] => 0 ) [#title] => [#description] => [#theme_used] => 1 [#printed] => 1 [#type] => [#value] => [#prefix] => [#suffix] => [#children] =>

• Headache, dizziness, nausea and vomiting, skin irritation, contact dermatitis, rash, itching, redness or swelling, burning or stinging sensation may occur.
• May cause hypersensitivity/allergic reactions in some individuals with sensitive skin

) [#title] => [#description] => [#children] =>

• Headache, dizziness, nausea and vomiting, skin irritation, contact dermatitis, rash, itching, redness or swelling, burning or stinging sensation may occur.
• May cause hypersensitivity/allergic reactions in some individuals with sensitive skin

[#printed] => 1 ) [#single] => 1 [#attributes] => Array ( ) [#required] => [#parents] => Array ( ) [#tree] => [#context] => full [#page] => 1 [#field_name] => field_side_effects [#title] => Side Effects [#access] => 1 [#label_display] => above [#teaser] => [#node] => stdClass Object *RECURSION* [#type] => content_field [#children] =>

• Headache, dizziness, nausea and vomiting, skin irritation, contact dermatitis, rash, itching, redness or swelling, burning or stinging sensation may occur.
• May cause hypersensitivity/allergic reactions in some individuals with sensitive skin

[#printed] => 1 ) [#title] => [#description] => [#children] =>
Side Effects: 

• Headache, dizziness, nausea and vomiting, skin irritation, contact dermatitis, rash, itching, redness or swelling, burning or stinging sensation may occur.
• May cause hypersensitivity/allergic reactions in some individuals with sensitive skin

[#printed] => 1 ) [field_storage] => Array ( [#type_name] => product [#context] => full [#field_name] => field_storage [#post_render] => Array ( [0] => content_field_wrapper_post_render ) [#weight] => 11 [field] => Array ( [#description] => [items] => Array ( [0] => Array ( [#formatter] => default [#node] => stdClass Object *RECURSION* [#type_name] => product [#field_name] => field_storage [#weight] => 0 [#theme] => text_formatter_default [#item] => Array ( [value] => • Store below 30 C° • Protect from light and freezing [format] => 1 [safe] =>

• Store below 30 C°
• Protect from light and freezing

[#delta] => 0 ) [#title] => [#description] => [#theme_used] => 1 [#printed] => 1 [#type] => [#value] => [#prefix] => [#suffix] => [#children] =>

• Store below 30 C°
• Protect from light and freezing

) [#title] => [#description] => [#children] =>

• Store below 30 C°
• Protect from light and freezing

[#printed] => 1 ) [#single] => 1 [#attributes] => Array ( ) [#required] => [#parents] => Array ( ) [#tree] => [#context] => full [#page] => 1 [#field_name] => field_storage [#title] => Storage [#access] => 1 [#label_display] => above [#teaser] => [#node] => stdClass Object *RECURSION* [#type] => content_field [#children] =>

• Store below 30 C°
• Protect from light and freezing

[#printed] => 1 ) [#title] => [#description] => [#children] =>
Storage: 

• Store below 30 C°
• Protect from light and freezing

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Methyl salicylate ointment : 1 tube/box-30g

[#delta] => 0 ) [#title] => [#description] => [#theme_used] => 1 [#printed] => 1 [#type] => [#value] => [#prefix] => [#suffix] => [#children] =>

Methyl salicylate ointment : 1 tube/box-30g

) [#title] => [#description] => [#children] =>

Methyl salicylate ointment : 1 tube/box-30g

[#printed] => 1 ) [#single] => 1 [#attributes] => Array ( ) [#required] => [#parents] => Array ( ) [#tree] => [#context] => full [#page] => 1 [#field_name] => field_packing [#title] => Packing [#access] => 1 [#label_display] => above [#teaser] => [#node] => stdClass Object *RECURSION* [#type] => content_field [#children] =>

Methyl salicylate ointment : 1 tube/box-30g

[#printed] => 1 ) [#title] => [#description] => [#children] =>
Packing: 

Methyl salicylate ointment : 1 tube/box-30g

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PDF: 
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Image: 
Brand Name: 

Mentodic®

Dosage Form: 

30g ointment (Each 100 g of ointment contains 14 g Methyl Salicylate and 10 g Menthol)

Pharmacological Category: 

Topical analgesics

Therapeutic Category: 

Anti-inflammatory drugs

Pregnancy Category: 

category B

Methyl salicylate is a salicylic acid derivative.Salicylates inhibit cyclooxygenase, thereby reducing the formation of prostaglandins.

Pharmacokinetics: 

• May be absorbed through intact skin.

• The absorption of topical salicylates is proportional to the surface area involved, duration of exposure, concentration and skin integrity.
• Absorption characteristics of salicylates vary with the dose, formulation and route of administration.
• Percutaneous absorption is enhanced by exercise, heat, occlusion, or disruption of the integrity of the skin or application to large areas of skin
• Both the rate and extent of absorption increases after repeated application;increasing the bioavailability.
• Methylsalicylateis extensively metabolised to salicylic acid in the dermal and subcutaneous tissues after topical application
• At therapeutic levels, the half life of salicylates is 2-4 hours.
• As salicylate level increase into the toxic range, the half-life can be greater than 18 hours.

Indications: 

• Provide symptomatic relief for mild to moderate muscular and joint aches and pains, muscle cramps, shoulder aches and stiff neck
• For the temporary relief of pain associated with rheumatism, arthritis, neuralgia, sprains and strains of joints and muscles, lumbago and fibrositis

Contraindications: 

• Do not use in patients with aspirin or salicylate idiosyncrasy.
• Hypersensitivity to any of the ingredients in the product.

Precautions: 

• Initially apply a small amount to a limited skin area and observe whether there is discomfort or itch before applying to a larger skin area. Discontinue use if irritation develops.
• For external use only; not to be taken.
• Avoid contact with the eyes and mucous membranes.
• Do not apply to open wounds or damaged skin.
• Avoid excessive use during pregnancy and lactation
• Do not apply over large areas of the body or bandageor use with heating pads.

Drug Interactions: 

• This product contains methyl salicylate and when applied or rubbed on to the skin, can be absorbed through the skin into the blood. For patients taking warfarin, excessive application on to the skin for muscle or joints pains may increase the chances of bleeding

Side Effects: 

• Headache, dizziness, nausea and vomiting, skin irritation, contact dermatitis, rash, itching, redness or swelling, burning or stinging sensation may occur.
• May cause hypersensitivity/allergic reactions in some individuals with sensitive skin

Storage: 

• Store below 30 C°
• Protect from light and freezing

Packing: 

Methyl salicylate ointment : 1 tube/box-30g

PDF: 
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CONTACT US:

Head Office:
Address: No.1, Beastoon Ave., Dr. Fatemi Sq., Tehran1431663135 Iran
Tel: (+98 21)-889 65323
Fax: (+98 21)-889 57056
Factory:
Address: Caspian tamin Pharmaceutical Co., Entrance 1, Rasht Industrial Zone, Rasht, Guilan, Iran
Tel: (+98 131) 338-2511- 8
Fax: (+98 131) 338 – 2517